Search results for "Portopulmonary hypertension"

showing 3 items of 3 documents

Portopulmonary hypertension.

2011

Portopulmonary hypertension (PPHT) is a respiratory complication of portal hypertension, defined as an increase in mean pulmonary artery pressure (PAP) of > 25 mmHg with an increase in pulmonary vascular resistance of > 240 dyn.s/cm-5 and a normal pulmonary capillary wedge pressure ( < 15 mmHg), which often occurs in subjects with liver cirrhosis. Histopathological features of PPHT are endothelial and smooth-muscle cell proliferation and fibrosis leading to luminal obstruction in the resistance arteries. The pathogenesis of PPHT may result from an imbalance between vasoconstrictor and vasodilating factors. The most common pulmonary symptom is exertional dyspnea; fatigue, chest pain…

Settore MED/09 - Medicina InternaHypertension PulmonaryHypertension Portalportopulmonary hypertensionHumansGeneral MedicineLiver TransplantationClinical and investigative medicine. Medecine clinique et experimentale
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Very Early Presentation of Extrahepatic Portal Vein Obstruction Causing Portal Hypertension in an Infant: Uncertainties in the Management and Therape…

2016

Extrahepatic portal vein obstruction, although rare in children, is a significant cause of portal hypertension (PHT) leading to life-threatening gastrointestinal bleeding in the pediatric age group. PHT may also lead to other complications such as hyperesplenism, cholangyopathy, ascites, and even hepatopulmonary syndrome and portopulmonary hypertension that may require organ transplantation. Herein we report the case of an asymptomatic 11-month-old infant wherein a hepatomegaly and cavernous transformation of the portal vein was detected by liver ultrasound. Neither signs of thrombosis in arteriovenous system, nor affectation of biliary tract were identified in the magnetic resonance imagin…

medicine.medical_specialtyFollow-up guidelinesPortal venous pressureSingle CaseEsophageal varices03 medical and health sciences0302 clinical medicineEsophageal varicesAscitesmedicinelcsh:RC799-869Hepatopulmonary syndromePortopulmonary hypertensionbusiness.industryGastroenterologyInfantCavernous transformation of portal veinmedicine.diseaseCollateral circulationThrombosisSurgery030220 oncology & carcinogenesisPortal hypertensionlcsh:Diseases of the digestive system. Gastroenterology030211 gastroenterology & hepatologyRadiologymedicine.symptombusinessCase Reports in Gastroenterology
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Clinical implications of the hyperdynamic syndrome in cirrhosis.

2014

Abstract The hyperdynamic syndrome is a late consequence of portal hypertension in cirrhosis. The principal hemodynamic manifestations of the hyperdynamic syndrome are high cardiac output, and increased heart rate and total blood volume, accompanied by reduced total systemic vascular resistance. Pathophysiology involves a complex of humoral and neural mechanisms that can determine hemodynamic changes, and lead to hyperdynamic circulation. In this review we focus our attention on the manifestations of the hyperdynamic syndrome. Some of these are well described and directly related to portal hypertension (varices, ascites, hepatic encephalopathy, and hepatorenal syndrome), while others, such …

Liver Cirrhosismedicine.medical_specialtyCirrhosisSettore MED/09 - Medicina InternaHeart DiseasesPortal venous pressureEsophageal and Gastric VaricesGastroenterologyHepatorenal syndromeHeart RateInternal medicineHypertension PortalInternal MedicinemedicineHumansCardiac Outputcirrhosis hepatorenal syndrome hyperdinamic syndrome cirrhotic cardiomyopathyHepatopulmonary syndromePortopulmonary hypertensionbusiness.industryHemodynamicsSyndromemedicine.diseaseCirrhotic cardiomyopathyHyperdynamic circulationCardiologyPortal hypertensionVascular Resistancebusiness
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